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- Writers: Frank Darabont
- Stars: Alanna Masterson , Andrew Lincoln , Chandler Riggs , Christian Serratos , Danai Gurira , Emily Kinney , Josh McDermitt , Lauren Cohan , Laurie Holden , Melissa McBride , Michael Cudlitz , Norman Reedus , Sarah Wayne Callies , Scott Wilson , Sonequa Martin-Green , Steven Yeun
People are dying in the prison with the outbreak and most of the survivors are in quarantine, including Glenn and Sacha. Meanwhile Tyreese is out of control asking Rick, Darryl and Carol to find who burnt to death David and Karen. Darryl drives Zach's car with Michonne, Tyreese and Bob to a rural university eighty miles far from the prison to seek antibiotics to heal the infected people. Carol goes outside the prison to unblock the water piping while Rick investigates the murder of David and Karen, coming to a surprising revelation.