- Writers: Jack Amiel, Michael Begler
- Stars: André Holland , Cara Seymour , Charles Aitken , Chris Sullivan , Clive Owen , Eric Johnson , Eve Hewson , Frank Wood , Grainger Hines , Happy Anderson , Jennifer Ferrin , Jeremy Bobb , Juliet Rylance , Leon Addison Brown , Lucas Papaelias , Maya Kazan , Michael Angarano , Perry Yung , Richard James Porter , Suzanne Savoy , Tom Lipinski , Ying Ying Li , Ylfa Edelstein , Zuzanna Szadkowski
Dr. Gillibrand returns to the Knick to find his social order upended. Dr. Edwards is now a working member of the team with Thackery's full support. They are using his suction machine and Bertie performs an operation using his written guide. Constable Phinny Sears is stabbed by an irate African-American after the policeman suggests to his girlfriend that she could work in one of Bunky Collier's brothels. Sears is taken to the Knick and after he dies the mob forces it's way in attacking black patients who have sought refuge there. To save them, the staff is forced to transport them to the black hospital through the rioting crowds. With the crisis passed, Edwards and Cornelia become intimate, as do Thackery and Nurse Elkins.