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In Syracuse, New York, twenty-five year old Molly Grandin has been missing for 24 hours. The BAU believe her disappearance mirrors that of Gail Langston, a woman found dead four months earlier. Besides the similarities in their lives - both older Syracuse University undergrads, both petite females, both from blue collar backgrounds - the actual disappearance is the same: their abandoned car found with an overnight bag packed for a several day excursion. If Gail's death holds true to Molly's situation, the BAU have thirty-six hours to find Molly before the unsub kills her. The team initially believe both Molly and Gail had a intimate relationship with the male unsub, until evidence points to the unsub being a woman, changing the unsub profile to a trusted female friend. The biggest obstacle in finding Molly may be both the Langston and Grandin families believing that guarding secrets may be more beneficial than telling the truth. Meanwhile, Prentiss gets in touch with another of her Interpol colleagues, Tsia Mosely, who eventually passes along some disturbing news.