Following the case and ultimate suicide of Frank and Jane, individuals within the BAU are in an uncomfortable position. As Frank's mission was a personal one against him in many respects, Gideon feels guilty for the death of his friend Sarah and others at the hand of Frank. The unit is under review by Hotch's boss Erin Strauss, who has told Hotch in no uncertain terms that she feels the unit's recklessness and disarray is his fault and that his days in the unit are numbered. And without anyone else's knowledge, Strauss has asked Prentiss, whose transfer into the BAU was arranged by her, to assist her not only in getting Hotch removed from his position but also to have him fired from the FBI altogether. In the meantime, work for the BAU continues. Their next case takes them to Flagstaff, Arizona where female brunette students at a liberal arts college are being murdered. Because the victims have had no defensive wounds, the BAU surmise that the unsub is someone who blends into life at the college. They initially believe this case is open and shut when they identify someone who fits the profile. But working through this case, individuals within the BAU begin arguing amongst themselves and begin doubting their own abilities in profiling. The outcome of this case, in addition to the case with Frank, makes Gideon ponder his future.